Current options and therapeutic strategies for the management of cancer

Authors

  • Abdul Hayee Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan
  • Hà Thị Việt Mỹ Department of Immunology, Faculty of Medicine, Academic Assembly, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan
  • Muhammad Rahil Aslam First Department of Internal Medicine, Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.
  • Aamir Sharif Department of System Emotional Science, Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan
  • Đặng Sơn Tùng Department of 2nd pathology, Graduate School of Innovative Life Science, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan

Keywords:

Anti-cancer activity, cancer, treatment options, medicinal plants, efficacy.

Abstract

The disease is thought to be a significant general medical problem in created and emerging nations. The high mortality related to particular kinds of illness (Lung, prostate, stomach, and colorectal) legitimizes a developing interest in the recognizable proof of new pharmacological specialists effective in malignant growth counteraction and treatment. A few strategies are accessible to treat disease like a medical procedure, chemotherapy, radiation treatment, immunotherapy, and monoclonal immunizer treatment. The decision of treatment relies on the area of the growth, grade of the cancer, the phase of the infection, and the overall condition of the patient. Plants are considered as the great wellspring of profoundly compelling traditional specialists for the therapy of many sorts of malignant growth. The restorative plants' phytochemical investigation has generally added to the disclosure of new anticancer medications. This article has been made to audit a few restorative plants utilized for the therapy of malignant growth and gives information about anticancer therapeutic plants, which are utilized by individuals in all around the Asian nations.

 

References

1. Gennari, C., D. Castoldi, and O. Sharon, Natural products with taxol-like anti-tumor activity: Synthetic approaches to eleutherobin and dictyostatin. Pure and applied chemistry, 2007. 79(2): p. 173-180.
2. Karmakar, S.R., S.J. Biswas, and A.R. Khuda-Bukhsh, Anti-carcinogenic potentials of a plant extract (Hydrastis canadensis): I. Evidence from in vivo studies in mice (Mus musculus). Asian Pac J Cancer Prev, 2010. 11(2): p. 545-51.
3. Organization, W.H., CancerStats cancer worldwide. England, Wales and Scotland. Geneva: World Health Organization, 2011.
4. Garcia, M., et al., Global cancer facts & figures 2007. Atlanta, GA: American cancer society, 2007. 1(3): p. 52.
5. Cancers, N., Facts sheet. World Health Organization, 2010.
6. Cragg, G.M. and D.J. Newman, Plants as a source of anti-cancer agents. Journal of ethnopharmacology, 2005. 100(1-2): p. 72-79.
7. Rao, G.V., et al., Folk medicines for anticancer therapy-a current status. Cancer Therapy, 2008. 6(2).
8. Enger, E., Concepts in Biology'2007 Ed. 2003: Rex Bookstore, Inc.
9. Hasan, R., Colorectal Cancer in Bangladesh: Demographic Details, Risk Factors, Diagnosis & Treatment Patterns. 2010, East West University.
10. Wanjek, C., Exciting New Cancer Treatments Emerge Amid Persistent Myths. Live Science, 2006.
11. Hayden, E.C., Cutting off cancer's supply lines. Nature, 2009. 458(7239): p. 686.
12. Kolata, G., Lack of study volunteers hobbles cancer fight. New York Times, 2009. 13.
13. Takimoto, C.H. and A. Awada, Safety and anti-tumor activity of sorafenib (Nexavar®) in combination with other anti-cancer agents: a review of clinical trials. Cancer chemotherapy and pharmacology, 2008. 61(4): p. 535-548.
14. Dolmans, D.E., D. Fukumura, and R.K. Jain, Photodynamic therapy for cancer. Nature reviews cancer, 2003. 3(5): p. 380-387.
15. Damodar, S., et al., Autologous Immune Enhancement Therapy (AIET) for a case of Acute Myeloid Leukemia (AML)-Our experience. J Stem Cells Regen Med, 2006. 1(12): p. 40-41.
16. Sivaraman, G., et al., Autologous Immune Enhancement therapy for Advanced Carcinoma of Pancreas-A Case Report. Journal of Stem Cells & Regenerative Medicine, 2008. 4(1): p. 13-13.
17. Kleinman, H.K. and G. Liau, Gene therapy for antiangiogenesis. 2001, Oxford University Press. p. 965-967.
18. Rajandeep, K., et al., Anticancer plants: a review. J Nat Prod Plant Resour, 2011. 1: p. 131-136.
19. Cunningham, A., An investigation of the herbal medicine trade in Natal/KwaZulu. 1988: Institute of Natural Resources, University of Natal.
20. Meyer, J., et al., Inhibition of herpes simplex virus type 1 by aqueous extracts from shoots of Helichrysum aureonitens (Asteraceae). Journal of ethnopharmacology, 1996. 52(1): p. 41-43.
21. Ravindranath, M.H., et al., Epicatechins purified from green tea (Camellia sinensis) differentially suppress growth of gender-dependent human cancer cell lines. Evidence-Based Complementary and Alternative Medicine, 2006. 3(2): p. 237-247.
22. Chockalingam, V., S.S. Kadali, and P. Gnanasambantham, Antiproliferative and antioxidant activity of Aegle marmelos (Linn.) leaves in Dalton's Lymphoma Ascites transplanted mice. Indian journal of pharmacology, 2012. 44(2): p. 225.
23. Yadav, V.R., et al., Boswellic acid inhibits growth and metastasis of human colorectal cancer in orthotopic mouse model by downregulating inflammatory, proliferative, invasive and angiogenic biomarkers. International journal of cancer, 2012. 130(9): p. 2176-2184.
24. Park, J.H., et al., Cancer chemoprotective effects of Curcuma xanthorrhiza. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 2008. 22(5): p. 695-698.
25. Fang, J.-B., et al., Antitumor constituents from Alternanthera philoxeroides. Journal of Asian natural products research, 2007. 9(6): p. 511-515.
26. Badami, S., et al., Antitumor activity of total alkaloid fraction of Solanum pseudocapsicum leaves. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 2003. 17(9): p. 1001-1004.
27. Ozaslan, M., et al., In vivo antitumoral effect of Plantago major L. extract on Balb/C mouse with Ehrlich ascites tumor. The American journal of Chinese medicine, 2007. 35(05): p. 841-851.
28. Hussain, T., et al., Evaluation of chemopreventive effect of Fumaria indica against N-nitrosodiethylamine and CCl4-induced hepatocellular carcinoma in Wistar rats. Asian Pacific Journal of Tropical Medicine, 2012. 5(8): p. 623-629.
29. Konrad, L., et al., Antiproliferative effect on human prostate cancer cells by a stinging nettle root (Urtica dioica) extract. Planta medica, 2000. 66(01): p. 44-47.
30. Haniadka, R., et al., Zingiber officinale (ginger) as an anti-emetic in cancer chemotherapy: a review. The Journal of Alternative and Complementary Medicine, 2012. 18(5): p. 440-444.
31. Albert-Baskar, A. and S. Ignacimuthu, Chemopreventive effect of Cynodon dactylon (L.) Pers. extract against DMH-induced colon carcinogenesis in experimental animals. Experimental and Toxicologic Pathology, 2010. 62(4): p. 423-431.
32. Kaur, K., et al., Studies on correlation of antimutagenic and antiproliferative activities of Juglans regia L. Journal of environmental pathology, toxicology and oncology, 2003. 22(1).
33. Tanaka, R., et al., Potential anti-tumor-promoting activity of 3α-Hydroxy-D: A-friedooleanan-2-one from the stem bark of Mallotus philippensis. Planta medica, 2008. 74(04): p. 413-416.
34. Mahata, S., et al., Anticancer property of Bryophyllum pinnata (Lam.) Oken. leaf on human cervical cancer cells. BMC complementary and alternative medicine, 2012. 12(1): p. 1-11.
35. Asano, M., et al., Synthesis of anti-tumor dimeric indole alkaloids in Catharanthus roseus was promoted by irradiation with near-ultraviolet light at low temperature. Bioscience, biotechnology, and biochemistry, 2010. 74(2): p. 386-389.
36. Manoharan, S., et al., Evaluation of anticarcinogenic effects of Clerodendron inerme on 7, 12-dimethylbenz (a) anthracene-induced hamster buccal pouch carcinogenesis. Singapore Med J, 2006. 47(12): p. 1038-1043.
37. Preethi, K., G. Kuttan, and R. Kuttan, Anti-tumour activity of Ruta graveolens extract. Asian Pacific Journal of Cancer Prevention, 2006. 7(3): p. 439.
38. Aruna, K. and V. Sivaramakrishnan, Anticarcinogenic effects of some Indian plant products. Food and Chemical Toxicology, 1992. 30(11): p. 953-956.
39. Mazzio, E.A. and K.F. Soliman, In vitro screening of tumoricidal properties of international medicinal herbs: part II. Phytotherapy Research, 2010. 24(12): p. 1813-1824.
40. Ho, Y.C., et al., Inhibitory effects of xanthohumol from hops (Humulus lupulus L.) on human hepatocellular carcinoma cell lines. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 2008. 22(11): p. 1465-1468.
41. Liu, Y.-L., et al., Isolation of potential cancer chemopreventive agents from Eriodictyon californicum. Journal of Natural Products, 1992. 55(3): p. 357-363.
42. Baskar, A.A., et al., Chemopreventive potential of β-sitosterol in experimental colon cancer model-an in vitro and in vivo study. BMC complementary and alternative medicine, 2010. 10(1): p. 1-10.
43. Chiang, H.-C., et al., Experimental antitumor agents from Solanum indicum L. Anticancer research, 1991. 11(5): p. 1911-1917.
44. Kumarappan, C. and S.C. Mandal, Antitumor activity of polyphenolic extract of Ichnocarpus frutescens. Experimental oncology, 2007.
45. Saini, M., P.K. Goyal, and G. Chaudhary, Anti-tumor activity of Aloe vera against DMBA/croton oil-induced skin papillomagenesis in Swiss albino mice. Journal of environmental pathology, toxicology and oncology, 2010. 29(2).
46. Adebayo, A., et al., Anticancer and antiradical scavenging activity of Ageratum conyzoides L.(Asteraceae). Pharmacognosy magazine, 2010. 6(21): p. 62.
47. Gupta, M., et al., Antitumor activity of methanolic extract of Cassia fistula L. seed against Ehrlich ascites carcinoma. Journal of ethnopharmacology, 2000. 72(1-2): p. 151-156.
48. Konopa, J., et al., Antitumor substances from Bryonia alba L. Neoplasma, 1966. 13(3): p. 335-338.
49. Huang, Q., et al., Anti‐cancer properties of anthraquinones from rhubarb. Medicinal research reviews, 2007. 27(5): p. 609-630.
50. Saraydin, S.U., et al., Antitumoral effects of Melissa officinalis on breast cancer in vitro and in vivo. Asian Pacific Journal of Cancer Prevention, 2012. 13(6): p. 2765-2770.
51. Li, J., et al., Aqueous extract of Solanum nigrum inhibit growth of cervical carcinoma (U14) via modulating immune response of tumor bearing mice and inducing apoptosis of tumor cells. Fitoterapia, 2008. 79(7-8): p. 548-556.
52. Shilpa, P., V. Sivaramakrishnan, and S.N. Devaraj, Induction of apoptosis by methanolic extract of Rubia cordifolia Linn in HEp-2 cell line is mediated by reactive oxygen species. Asian Pacific Journal of Cancer Prevention, 2012. 13(6): p. 2753-2758.
53. Biswas, S., N. Bhattacharjee, and A. Khuda-Bukhsh, Efficacy of a plant extract (Chelidonium majus L.) in combating induced hepatocarcinogenesis in mice. Food and Chemical Toxicology, 2008. 46(5): p. 1474-1487.
54. Liu, W., et al., Inhibition of tumor growth in vitro by a combination of extracts from rosa roxburghii tratt and fagopyrum cymosum. Asian Pacific Journal of Cancer Prevention, 2012. 13(5): p. 2409-2414.
55. Manu, K. and G. Kuttan, Anti-metastatic potential of Punarnavine, an alkaloid from Boerhaavia diffusa Linn. Immunobiology, 2009. 214(4): p. 245-255.
56. Liu, J., et al., Senescence effects of Angelica sinensis polysaccharides on human acute myelogenous leukemia stem and progenitor cells. Asian Pacific Journal of Cancer Prevention, 2013. 14(11): p. 6549-6556.
57. Lima, S.R., et al., In vivo and in vitro studies on the anticancer activity of Copaifera multijuga Hayne and its fractions. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 2003. 17(9): p. 1048-1053.
58. da Costa, P.M., et al., Antiproliferative activity of pristimerin isolated from Maytenus ilicifolia (Celastraceae) in human HL-60 cells. Toxicology in vitro, 2008. 22(4): p. 854-863.
59. Rajendran, N. and N. Deepa, Anti-tumor activity of Acanthospermum hispidum DC on dalton ascites lymphoma in mice. Natural Product Sciences, 2007. 13(3): p. 234-240.
60. Mothe, C.G., I.A. De Souza, and G.M. Calazans, Antitumor activity of cashew gum from Anacardium occidentale L. Agro Food Industry Hi-Tech, 2008. 19(6): p. 50-52.
61. Rajkapoor, B., et al., Chemoprevention and cytotoxic effect of Bauhinia variegata against N-nitrosodiethylamine induced liver tumors and human cancer cell lines. Journal of ethnopharmacology, 2006. 104(3): p. 407-409.
62. Yahayo, W., A. Supabphol, and R. Supabphol, Suppression of human fibrosarcoma cell metastasis by Phyllanthus emblica extract in vitro. Asian Pacific Journal of Cancer Prevention, 2013. 14(11): p. 6863-6867.
63. Hematulin, A., et al., Ethanolic extract from Derris scandens Benth mediates radiosensitzation via two distinct modes of cell death in human colon cancer HT-29 cells. Asian Pacific Journal of Cancer Prevention, 2014. 15(4): p. 1871-1877.
64. Bharali, R., J. Tabassum, and M.R.H. Azad, Chemomodulatory effect of Moringa oleifera, Lam, on hepatic carcinogen metabolising enzymes, antioxidant parameters and skin papillomagenesis in mice. Asian Pacific Journal of Cancer Prevention, 2003. 4(2): p. 131-140.
65. Sigurdsson, S., et al., Antitumour activity of Angelica archangelica leaf extract. in vivo, 2005. 19(1): p. 191-194.
66. George, V.C., et al., Quantitative assessment of the relative antineoplastic potential of the n-butanolic leaf extract of Annona muricata Linn. in normal and immortalized human cell lines. Asian Pacific Journal of Cancer Prevention, 2012. 13(2): p. 699-704.
67. Gurunagarajan, S. and B. Pemaiah, Anti-tumor and antioxidant potentials of ethanolic extract of Leonotis nepetefolia R. Br. against Ehrlich Ascites carcinoma cell lines. J. Pharm. Res, 2010. 3(12): p. 2990-2992.
68. Choedon, T., et al., Anticancer and cytotoxic properties of the latex of Calotropis procera in a transgenic mouse model of hepatocellular carcinoma. World Journal of Gastroenterology: WJG, 2006. 12(16): p. 2517.
69. Endrini, S., et al., Comparing of the cytotoxicity properties and mechanism of Lawsonia inermis and Strobilanthes crispus extract against several cancer cell lines. J Med Sci, 2007. 7(7): p. 1098-1102.
70. Jing, J., Y. Ruolin, and L. Yang, The anticancer activity of compounds in lipophilic fraction of Daucus carota. Journal of Guiyang Medical College, 2008. 5: p. 014.
71. Alabsi, A.M., et al., Induction of caspase-9, biochemical assessment and morphological changes caused by apoptosis in cancer cells treated with goniothalamin extracted from Goniothalamus macrophyllus. Asian Pacific Journal of Cancer Prevention, 2013. 14(11): p. 6273-6280.
72. Li, K. and T. Zhang, Effect of procyanidins from Pinus koraiensis bark on growth inhibition and expression of PCNA and TNF-[alpha][alpha] in mice with U14 cervical cancer. Clinical Practice, 2007. 4(5): p. 685.
73. Zhang, H., et al., Anticancer activity of limonoid from Khaya senegalensis. Phytotherapy Research, 2007. 21(8): p. 731-734.
74. Sakthive, K., et al., Anticancer activity of Acacia nilotica (L.) Wild. Ex. Delile subsp. indica against Dalton's ascitic lymphoma induced solid and ascitic tumor model. Asian Pacific Journal of Cancer Prevention, 2012. 13(8): p. 3989-3995.
75. Sreelatha, S., E. Dinesh, and C. Uma, Antioxidant properties of Rajgira (Amaranthus paniculatus) leaves and potential synergy in chemoprevention. Asian Pacific Journal of Cancer Prevention, 2012. 13(6): p. 2775-2780.

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Published

2022-03-31

How to Cite

Hayee, A., Việt Mỹ, H. T. ., Aslam, M. R. ., Sharif, A., & Tùng, Đặng S. . (2022). Current options and therapeutic strategies for the management of cancer. International Journal of Natural Medicine and Health Sciences, 1(2). Retrieved from https://journals.iub.edu.pk/index.php/ijnms/article/view/832