Plant-Derived bioactive compounds as Skin Photo protection Agents
DOI:
https://doi.org/10.52461/ijnms.v1i2.866Keywords:
Photoprotection, bioactive compounds, UV radiations, SkinAbstract
Exposure to the sun is unavoidable in daily life. Ultra-violet radiations are the major component of sunlight and play a significant role in damaging the skin. They induce many skin problems like erythema, sun burn, rashes as well as skin cancer. Although the protective layer of earth, the ozone layer, filters most of the damaging radiations from the sun, with the dramatic rise in pollution, global warming is reaching at its peak point. These pollutants deteriorate the protective ozone layer of earth, resulting in its thinning which in turn allows the passage of hazardous solar radiations to the earth. These radiations act as the most potent irritant for the skin cells. In order to avoid these hazardous effects of UV radiations, there is an emerging demand for the use of photo protectants. Manufacturers of various cosmetic and skin care companies are focusing on natural compounds to deal with skin problems caused by UV radiations. It includes phytochemicals and bioactive compounds from the plants. As these are natural and economic, they don’t leave any damaging effect on the body and are the best photo protectants against UV radiations. There are several plants with their chemical compounds derived and studied for their photoprotective role. Most of them are proven best for cosmetic remedies. This review will provide a look over the plant-derived bioactive compounds of Southeast Asia with their photo protectant effect.
References
Lawton, S. "Skin 1: the structure and functions of the skin." Nurs. Times 115 (2019): 30-33.
Nor, Norazirah Md, and Mazlin M. Baseri. "Skin and subcutaneous infections in south-east Asia." Current opinion in infectious diseases 28.2 (2015): 133-138.
Cruz, Ponciano D., and Paul R. Bergstresser. "Photoimmunology: Effects of Ultraviolet B Radiation on Cutaneous Photocarcinogenesis and Allergic Contact Sensitivity." Clinical Photomedicine. Routledge, 2018. 137-151.
Cavinato, Maria, et al. "Plant extracts and natural compounds used against UVB-induced photoaging." Biogerontology 18.4 (2017): 499-516.
Wright, Fiona, and Richard B. Weller. "Risks and benefits of UV radiation in older people: More of a friend than a foe?." Maturitas 81.4 (2015): 425-431.
Siiskonen, Hanna, et al. "Ultraviolet radiation and skin mast cells: Effects, mechanisms and relevance for skin diseases." Experimental Dermatology 27.1 (2018): 3-8.
Maddu, Narendra. "Diseases related to types of free radicals." Antioxidants. Rijeka, Croatia: IntechOpen, 2019.
Peña-Bautista, Carmen, et al. "Free radicals in Alzheimer's disease: Lipid peroxidation biomarkers." Clinica Chimica Acta 491 (2019): 85-90.
Liguori, Ilaria, et al. "Oxidative stress, aging, and diseases." Clinical interventions in aging 13 (2018): 757.
Jakubczyk, K., Dec, K., Kałduńska, J., Kawczuga, D., Kochman, J., & Janda, K. (2020). Reactive oxygen species-sources, functions, oxidative damage. Polski merkuriusz lekarski: organ Polskiego Towarzystwa Lekarskiego, 48(284), 124-127.
Żukowski P, Maciejczyk M, Waszkiel D. Sources of free radicals and oxidative stress in the oral cavity. Archives of Oral Biology. 2018 Aug 1;92:8-17.
Gabros S, Nessel TA, Zito PM. Sunscreens and photoprotection.(2019)
Parrado C, Philips N, Gilaberte Y, Juarranz A, González S. Oral photoprotection: effective agents and potential candidates. Frontiers in medicine. 2018 Jun 26;5:188.
Nahhas AF, Abdel‐Malek ZA, Kohli I, Braunberger TL, Lim HW, Hamzavi IH. The potential role of antioxidants in mitigating skin hyperpigmentation resulting from ultraviolet and visible light‐induced oxidative stress. Photodermatology, photoimmunology & photomedicine. 2019 Nov;35(6):420-8.
Noda Y. Antioxidant activity of nasunin, an anthocyanin in
eggplant peels. Toxicology 2000;148:119-23.
Rhodes, L.E.; O’Farrell, S.; Jackson, M.J.; Friedmann, P.S. Dietary fish-oil supplementation in humans reduces UVB-erythemal
sensitivity but increases epidermal lipid peroxidation. J. Investig. Derm. 1994, 103, 151–154.
Darr, D.; Dunston, H.; Faust, H.; Pinnell, S. Effectiveness of antioxidants (vitamin C and E) with and without sunscreens as topical
photoprotectants. Acta Derm. Venereol. 1996, 76, 264–268.
Mignon C, Uzunbajakava NE, Castellano‐Pellicena I, Botchkareva NV, Tobin DJ. Differential response of human dermal fibroblast subpopulations to visible and near‐infrared light: Potential of photobiomodulation for addressing cutaneous conditions. Lasers in Surgery and Medicine. 2018 Oct;50(8):859-82.
Tsoureli-Nikita, E.; Hercogova, J.; Lotti, T.; Menchini, G. Evaluation of dietary intake of vitamin E in the treatment of atopic dermatitis: A study of the clinical course and evaluation of the immunoglobulin E serum levels. Int. J. Dermatol. 2002, 41, 146–150.
Abraham, A.; Kattoor, A.J.; Saldeen, T.; Mehta, J.L. Vitamin E and its anticancer effects. Crit. Rev. Food. Sci. Nutr. 2019, 59, 2831–2838.
Lee, G.Y.; Han, S.N. The role of Vitamin E in Immunity. Nutrients 2018, 10, 1614
Panich, U.; Tangsupa-a-nan, V.; Onkoksoong, T.; Kongtaphan, K.; Kasetsinsombat, K.;
Akarasereenont, P.;Wongkajornsilp, A. Inhibition of UVA-mediated Melanogenesis by Ascorbic Acid through Modulation of Antioxidant Defense and Nitric Oxide System. Arch. Pharm. Res. 2011, 34, 811–820.
Eberlein-König, B.; Ring, J. Relevance of vitamins C and E in cutaneous photoprotection. J. Cosmet. Dermatol. 2005, 4, 4–9.
Placzek, M.; Gaube, S.; Kerkmann, U.; Gilbertz, K.P.; Herzinger, T.; Haen, E.; Przybilla, B. Ultraviolet B-induced DNA damage in human epidermis is modified by the antioxidants ascorbic acid and D-alpha-tocopherol. J. Investig. Dermatol. 2005, 124, 304–307.
Ferreira, R.; Napoli, J.; Enver, T.; Bernardino, L.; Ferrrira, L. Advances and challenges in retinoid delivery systems in regenerative and therapeutic medicine. Nat. Commun. 2020, 1, 4265.
Pullar, J.M.; Carr, A.C.; Vissers, M.C.M. The roles of vitamin C in skin health. Nutrients 2017, 9, 866–892.
Mirzoeva S, Tong X, Bridgeman BB, Plebanek MP, Volpert OV. Apigenin inhibits UVB-induced skin carcinogenesis: the role of thrombospondin-1 as an anti-inflammatory factor. Neoplasia. 2018 Sep 1;20(9):930-42.
Imran M, Aslam Gondal T, Atif M, Shahbaz M, Batool Qaisarani T, Hanif Mughal M, Salehi B, Martorell M, Sharifi‐Rad J. Apigenin as an anticancer agent. Phytotherapy Research. 2020 Aug;34(8):1812-28.
Tsuda T. Mechanism for the peroxynitrite scavenging activity by anthocyanins. FEBS Lett 2000;484:207-10.
Corrales-García JE, del Rosario García-Mateos M, Martínez-López E, Barrientos-Priego AF, Ybarra-Moncada MC, Ibarra-Estrada E, Méndez-Zúñiga SM, Becerra-Morales D. Anthocyanin and oil contents, fatty acids profiles and antioxidant activity of Mexican landrace avocado fruits. Plant Foods for Human Nutrition. 2019 Jun;74(2):210-5.
Sumaiyah S. Formulation and Evaluation of Skin Anti-aging Nanocream Containing Canola (Brassica napus L.) Oil. Indonesian Journal of Pharmaceutical and Clinical Research. 2021 May 28;4(1):47-58.
Elshaer M, Chen Y, Wang XJ, Tang X. Resveratrol: An overview of its anti-cancer mechanisms. Life sciences. 2018 Aug 15;207:340-9.
Lin MH, Hung CF, Sung HC, Yang SC, Yu HP, Fang JY. The bioactivities of resveratrol and its naturally occurring derivatives on skin. Journal of Food & Drug Analysis. 2021 Jan 1;29(1).
Rauf A, Imran M, Khan IA, ur‐Rehman M, Gilani SA, Mehmood Z, Mubarak MS. Anticancer potential of quercetin: A comprehensive review. Phytotherapy Research. 2018 Nov;32(11):2109-30.
Xu D, Hu MJ, Wang YQ, Cui YL. Antioxidant activities of quercetin and its complexes for medicinal application. Molecules. 2019 Jan;24(6):1123.
Almatroodi SA, Alsahli MA, Almatroudi A, Verma AK, Aloliqi A, Allemailem KS, Khan AA, Rahmani AH. Potential therapeutic targets of quercetin, a plant flavonol, and its role in the therapy of various types of cancer through the modulation of various cell signaling pathways. Molecules. 2021 Jan;26(5):1315.
Iqbal B, Ali J, Ganguli M, Mishra S, Baboota S. Silymarin-loaded nanostructured lipid carrier gel for the treatment of skin cancer. Nanomedicine. 2019 Jan;14(9):1077-93.
Chamayou‐Robert C, DiGiorgio C, Brack O, Doucet O. Blue light induces DNA damage in normal human skin keratinocytes. Photodermatology, photoimmunology & photomedicine. 2022 Jan;38(1):69-75.
Pourang A, Tisack A, Ezekwe N, Torres AE, Kohli I, Hamzavi IH, Lim HW. Effects of visible light on mechanisms of skin photoaging. Photodermatology, photoimmunology & photomedicine. 2021 Sep 29.
Bocheva G, Slominski RM, Janjetovic Z, Kim TK, Böhm M, Steinbrink K, Reiter RJ, Kleszczyński K, Slominski AT. Protective Role of Melatonin and Its Metabolites in Skin Aging. International Journal of Molecular Sciences. 2022 Jan;23(3):1238.
Zhang S, Duan E. Fighting against skin aging: the way from bench to bedside. Cell transplantation. 2018 May;27(5):729-38.
Hong JY, Han HS, Youn JH, Kim HW, Ryu HS, Park KY. Irradiation with 590‐nm yellow light‐emitting diode light attenuates oxidative stress and modulates UVB induced change of dermal fibroblasts. Experimental Dermatology. 2022 Feb 18.
Khan AQ, Travers JB, Kemp MG. Roles of UVA radiation and DNA damage responses in melanoma pathogenesis. Environmental and molecular mutagenesis. 2018 Jun;59(5):438-60.
Wang PW, Hung YC, Lin TY, Fang JY, Yang PM, Chen MH, Pan TL. Comparison of the Biological Impact of UVA and UVB upon the Skin with Functional Proteomics and Immunohistochemistry. Antioxidants. 2019 Dec;8(12):569.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 International Journal of Natural Medicine and Health Sciences
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
You are free to:
• Share: copy and redistribute the material in any medium or format.
• Adapt: remix, transform, and build upon the material.
• Attribution: You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
• NonCommercial: You may not use the material for commercial purposes.
• No additional restrictions: You may not apply legal terms or technological measures, that legally restrict others from doing anything the license permits.
